Epidemiological corroboration exhibits that fruits, vegetables and pulses have been associated with beneficial effects on human health such as decrease the risk of cancer and various chronic diseases.Chalcone is a vital component widely distributed naturally, which contributes more to human health because of its multiple biological activities. Some of the naturally occurringchalcones identified from plants are butein, xanthoangelol, cardamonin, naringenin and 4-hydroxy derricin are associated with antifungal, anticancer, antibacterial, antiviral, anti-inflammatory, and anti-diabetic and antioxidant activities. Chalcones and its derivatives find applications in the field of organic synthesis and leads to the evaluation of new product possessing intensified biological activity. Apart from chalcones other chemical components such as coumarin, imidazole, diazepam, ionone, indole and boronic acid exhibits various biological activity. This review article discussed about the various biological potential of chalcone hybrids, of more particular, the hybrids of chalcones exhibiting intensified anticancer properties over various cancer cell lines. This review evinced the consequence of heterocyclic fused chalcone hybrids has a potential biological compounds for various activity.
